Journal of Oral Science & Rehabilitation, Vol. 3

Induced pluripotent stem cells (iPSCs) possess high pluripotency and differentiation potential and may constitute a possible source of autologous stem cells for clinical applications. However, the lengthy reprogramming process (up to one month) remains one of the most significant challenges facing standard virus-mediated methodology. The Gli-like transcription factor Glis1 is highly expressed in unfertilized eggs and one-cell-stage embryos. In this study, iPSCs were generated using a combination of primary human oral mucosal fibroblasts (HOFs) and episomal plasmid vectors expressing transcription factors, including Glis1.

Journal of Oral Science & Rehabilitation, Vol. 3

The objective of this article is to describe the successful management of an apicomarginal defect of a maxillary lateral incisor with a bone block graft performed simultaneously with apical surgery of both lateral and central incisors.

Journal of Oral Science & Rehabilitation, Vol. 3

Platelet-rich plasma (PRP) gel is an autogenous blood-derived material that may be used as a regenerative agent of oral structures. The regenerative capacity of PRP is largely attributed to its composition, including many different growth factors. Thus far, no study has identified the molecular content of this gel. Therefore, it was the purpose of this study to assess the presence of different growth factors in PRP gel, using the Western blot technique.

Journal of Oral Science & Rehabilitation, Vol. 3

The objectives of this study are to review the properties of melatonin in regulating bone homeostasis; to discuss its direct and indirect effects on bone; and to propose mechanisms for the use of melatonin as an agent to promote alveolar bone regeneration.

Journal of Oral Science & Rehabilitation, Vol. 3

The patient’s awareness and knowledge of periodontal disease is a key factor for successful periodontal treatment. The objective of this study was to evaluate this knowledge among patients referred to a specialist periodontal clinic.

Journal of Oral Science & Rehabilitation, Vol. 3

The objective of this study was to assess spontaneous bone healing after enucleation of large jaw cysts without using any grafting material.

Journal of Oral Science & Rehabilitation, Vol. 3

All-on-4 treatment concept is widely applied for complete-arch rehabilitations. Nevertheless, minor technical and biological complications can occur. The objective of this study was to evaluate the three-year clinical and radiographic data of complete-arch fixed dental prostheses supported by four implants according to the All-on-4 protocol.

Journal of Oral Science & Rehabilitation, Vol. 2

This is a five-year follow-up study of a previous investigation with the aim of assessing the esthetic outcome of Morse taper implants used to replace congenitally missing lateral incisors after orthodontic treatment.

Journal of Oral Science & Rehabilitation, Vol. 2

The objective of this study was compare the clinical results of the coronally advanced flap (CAF) without vertical releasing incisions using ( i ) a tunneling procedure on the maxillary midline papilla (test) or ( ii ) a conventional technique (control) in which the midline papilla is incised and elevated like any other papilla in the procedure.

Journal of Oral Science & Rehabilitation, Vol. 2

The objective of this study was to establish the primary stability of implants with two different designs placed into artificial bone (Type II and Type IV density) by clinicians with different levels of experience using the same implant bed preparation protocol.